Mechanochemistry of supramolecules

• Anima Bose and
• Prasenjit Mal

Beilstein J. Org. Chem. 2019, 15, 881–900, doi:10.3762/bjoc.15.86

• as the solvent-free condition may make traditional workup superfluous [31][32]. Also, mechanochemical methods have high impact in ecology and economy as they save time [33]. Mechanochemical syntheses benefit from high to quantitative conversions, minimized steps for purification and diminished

A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes

• Yong Miao,
• Florence Djedaïni-Pilard and
• Véronique Bonnet

Beilstein J. Org. Chem. 2014, 10, 2654–2657, doi:10.3762/bjoc.10.278

• high reactant concentration and high temperatures used. The yield of the reaction performed in solvent-free condition is slightly lower than those obtained when conducted in DMF. This may be linked to the purification, since a large quantity of succinic anhydride was used in the reaction. Excess

Silica sulfuric acid: a reusable solid catalyst for one pot synthesis of densely substituted pyrrole-fused isocoumarins under solvent-free conditions

• Sudipta Pathak,
• Kamalesh Debnath and
• Animesh Pramanik

Beilstein J. Org. Chem. 2013, 9, 2344–2353, doi:10.3762/bjoc.9.269

• starting materials, and the excellent yields of products. Keywords: green chemistry; pyrrole-fused isocoumarin; reusable solid support; silica sulfuric acid; solvent-free condition; Introduction Isocoumarins are an important class of naturally occurring lactones [1][2][3], which has attracted the

Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization

• Ryan Pearson,
• Shuyu Zhang,
• Gang He,
• Nicola Edwards and
• Gong Chen

Beilstein J. Org. Chem. 2013, 9, 891–899, doi:10.3762/bjoc.9.102

• . We commenced the study by investigating the arylation of 2-methoxybenzyl picolinamide 1 with 4-iodoanisole (2) under various conditions (Table 1) to form our desired arylated product 3. Our initial attempt under the original Pd(OAc)2-catalyzed AgOAc-promoted solvent-free condition afforded the